Description

Boc-Lys(Z)-Oh Dcha is a protected amino acid derivative widely used as a critical building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates to ensure the fidelity and yield of complex peptide sequences. It is primarily utilized in the pharmaceutical, biotechnology, and life science research sectors for the development of novel therapeutic peptides and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of lysine residues with orthogonal side-chain protection.
• Solution-Phase Peptide Synthesis: Used in classical coupling reactions for constructing peptide fragments in solution.
• Pharmaceutical Research & Development: Serves as a crucial raw material in the R&D of peptide-based drugs, hormones, and diagnostic agents.
• Bioconjugation: Facilitates the site-specific modification of peptides and proteins for creating antibody-drug conjugates (ADCs) or labeled biomolecules.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new bioactive peptide leads.
• Academic & Institutional Research: Used in university and institutional labs for fundamental studies in biochemistry, medicinal chemistry, and chemical biology.

Basic Information

Item	Details
Product Name	Boc-Lys(Z)-Oh Dcha
CAS No.	16948-04-2
Molecular Formula	C26H42N2O6
Molecular Weight	478.63 g/mol
Synonyms	Nα-Boc-Nε-Cbz-L-lysine; Boc-Lys(Z)-OH; Nα-(tert-Butoxycarbonyl)-Nε-(benzyloxycarbonyl)-L-lysine; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)hexanoic acid (common mis-association); Boc-Lys(Cbz)-OH; Fmoc-Lys(Boc)-OH (related, but different); N-Boc-N'-Cbz-L-lysine; BOC-LYS(Z)-OH DCHA Salt
EINECS	Contact for details

Quality Control

Our Boc-Lys(Z)-Oh Dcha is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the stringent requirements for peptide synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Optical Rotation [α]D20	-10.0° to -12.0° (c=1 in DMF)
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.