Description

Boc-Hocys(Bzl)-Oh CAS NO 16947-99-2 is a protected cysteine derivative, specifically Nα-Boc-S-benzyl-L-cysteine, widely used as a critical building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring precise control over side-chain reactivity and orthogonal deprotection strategies. It is primarily utilized by the pharmaceutical, biotechnology, and life sciences industries for the development of therapeutic peptides, research biochemicals, and complex organic molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of cysteine residues with orthogonal protecting groups.
• Pharmaceutical Research & Development: Used in the synthesis of peptide-based drug candidates, including those targeting metabolic and neurological disorders.
• Bioconjugation: Serves as a precursor for creating thiol-reactive linkers or for introducing specific functional handles onto biomolecules.
• Chemical Biology Probes: Employed in the construction of labeled peptides for studying protein-protein interactions and enzyme mechanisms.
• Custom Peptide Services: A fundamental raw material for CROs and CDMOs offering bespoke peptide manufacturing.
• Material Science: Potential use in synthesizing peptide-based polymers or surface-modifying agents.

Basic Information

Product Name	Boc-Hocys(Bzl)-Oh
CAS No.	16947-99-2
Molecular Formula	C15H21NO4S
Molecular Weight	311.40 g/mol
Synonyms	Nα-Boc-S-benzyl-L-cysteine; Boc-Cys(Bzl)-OH; (R)-2-((tert-Butoxycarbonyl)amino)-3-(benzylthio)propanoic acid; N-(tert-Butoxycarbonyl)-S-benzyl-L-cysteine; Boc-L-cysteine(S-benzyl); BOC-CYS(BZL)-OH; Boc-Cys(Bzl); tert-Butyloxycarbonyl-S-benzyl-L-cysteine
EINECS	Contact for details

Quality Control

Our Boc-Hocys(Bzl)-Oh is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and cGMP manufacturing environments. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material supporting DMF or CMC documentation upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation [α]20/D	-15.0° to -20.0° (c=1 in Acetic Acid)
Loss on Drying	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.