Description

Boc-2-Amino-4-(Ethyl(Thio))Butyric Acid CAS NO 16947-91-4 is a protected amino acid derivative featuring a tert-butoxycarbonyl (Boc) group and a unique ethylthio side chain. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled introduction of non-proteinogenic amino acids to modify peptide properties. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers developing novel therapeutic peptides, peptidomimetics, and bioactive compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Serves as a protected amino acid building block in Fmoc/t-Bu and Boc/Bzl solid-phase and solution-phase peptide synthesis strategies.
• Research & Development: Used in academic and industrial R&D for exploring structure-activity relationships (SAR) by incorporating sulfur-containing side chains into peptide sequences.
• Bioconjugation: The reactive functional groups allow for use in creating peptide conjugates for drug delivery systems or diagnostic probes.
• Production of Custom Peptides: Essential for contract research and manufacturing organizations (CROs/CMOs) producing bespoke peptides for clients.
• Chemical Biology Probes: Utilized in the development of chemical tools to study enzyme function and protein-protein interactions.

Basic Information

Product Name	Boc-2-Amino-4-(Ethyl(Thio))Butyric Acid
CAS No.	16947-91-4
Molecular Formula	C11H21NO4S
Molecular Weight	263.35 g/mol
Synonyms	Boc-S-Ethylhomocysteine; N-(tert-Butoxycarbonyl)-S-ethylhomocysteine; (R/S)-2-[(tert-Butoxycarbonyl)amino]-4-(ethylthio)butanoic Acid; Boc-DL-S-Ethylhomocysteine; 2-[(tert-Butoxycarbonyl)amino]-4-(ethylsulfanyl)butanoic Acid; N-Boc-S-ethyl-L-homocysteine; Boc-S-Ethyl-DL-homocysteine; 4-(Ethylthio)-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid
EINECS	Contact for details

Quality Control

Our Boc-2-Amino-4-(Ethyl(Thio))Butyric Acid is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and synthesis. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.