Description

Boc-D-Orn(Z)-Oh is a protected derivative of the non-proteinogenic amino acid D-ornithine, featuring both Boc (tert-butoxycarbonyl) and Z (benzyloxycarbonyl) protecting groups. This compound is a crucial chiral building block in the synthesis of complex peptides and peptidomimetics, enabling precise control over stereochemistry and sequence. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers developing therapeutic peptides, diagnostic agents, and novel bioactive compounds.

Application

• Pharmaceutical Intermediates: Key chiral synthon for the solid-phase and solution-phase synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Research: Essential building block in academic and industrial R&D for constructing peptides with specific D-amino acid configurations to enhance metabolic stability.
• Bioconjugation: Used in the preparation of labeled peptides and protein conjugates for diagnostic and biochemical research applications.
• Combinatorial Chemistry: A valuable component in libraries for high-throughput screening to discover new lead compounds with modified peptide backbones.
• Prodrug Development: Serves as a precursor for designing prodrugs where the protecting groups are cleaved under specific physiological conditions.

Basic Information

Product Name	Boc-D-Orn(Z)-Oh
CAS No.	16937-92-1
Molecular Formula	C₁₈H₂₆N₂O₆
Molecular Weight	366.41 g/mol
Synonyms	N2-[(Benzyloxy)carbonyl]-N5-[(1,1-dimethylethoxy)carbonyl]-D-ornithine; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-((tert-butoxycarbonyl)amino)pentanoic acid; Boc-D-Orn(Z)-OH; Boc-D-Orn(Bzl)-OH; Nα-Boc-Nδ-Z-D-ornithine; D-Orn(Boc,Z)-OH; Nδ-Z-Nα-Boc-D-ornithine; tert-Butyl N-[(2R)-5-{[(benzyloxy)carbonyl]amino}-1-carboxypentyl]carbamate
EINECS	Contact for details

Quality Control

Our Boc-D-Orn(Z)-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); ensure the container is kept sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.