Description

(1-Chloro-2,2,2-Trifluoro-1-Trifluoromethyl-Ethyl)-Benzene is a specialized fluorinated aromatic intermediate of significant interest in advanced organic synthesis. Its unique structure, featuring a high concentration of fluorine atoms, makes it a valuable precursor for introducing trifluoromethyl and related perfluoroalkyl groups into target molecules. This compound is primarily sought by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced metabolic stability and lipophilicity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring trifluoromethylphenyl or related fluorinated motifs to modulate bioavailability and potency.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where fluorine incorporation improves weatherfastness and biological activity.
• Liquid Crystal & OLED Materials: Serves as a fluorinated core unit in the production of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Imparts unique properties such as chemical resistance, low surface energy, and thermal stability when incorporated into high-performance polymers and coatings.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and as a source of fluorinated carbenes or other reactive species in complex molecular construction.

Basic Information

Item	Details
Product Name	(1-Chloro-2,2,2-Trifluoro-1-Trifluoromethyl-Ethyl)-Benzene
CAS No.	16878-50-5
Molecular Formula	C9H5ClF6
Molecular Weight	262.58 g/mol
Synonyms	1-Chloro-2,2,2-trifluoro-1-(trifluoromethyl)ethylbenzene; α-Chloro-α-(trifluoromethyl)benzotrifluoride; (1-Chloro-2,2,2-trifluoro-1-trifluoromethylethyl)benzene; Benzene, (1-chloro-2,2,2-trifluoro-1-(trifluoromethyl)ethyl)-; 1-Chloro-1-phenyl-2,2,2-trifluoro-1-(trifluoromethyl)ethane; Phenyl(trifluoromethyl)chlorodifluoromethane (related); TFAB-CF3 derivative
EINECS	Contact for details

Quality Control

Our (1-Chloro-2,2,2-Trifluoro-1-Trifluoromethyl-Ethyl)-Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.45 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.