Description

(S)-3-Phenylalanine T-Butyl Ester is a high-purity chiral building block and protected amino acid derivative essential for advanced organic synthesis. This compound is critical for ensuring stereochemical integrity in the production of complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of peptide-based therapeutics, enzyme inhibitors, and other fine chemicals where precise chirality is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Peptide Synthesis: Serves as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis for research and development.
• Protease Inhibitor Development: Used in the design and construction of selective enzyme inhibitors targeting various proteases.
• Chemical Biology Research: Employed as a tool compound for studying protein-protein interactions and metabolic pathways.
• Asymmetric Catalysis: Acts as a chiral auxiliary or ligand precursor in catalytic asymmetric transformations.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals and advanced materials requiring specific stereochemistry.

Basic Information

Product Name	(S)-3-Phenylalanine T-Butyl Ester
CAS No.	16874-17-2
Molecular Formula	C₁₃H₁₉NO₂
Molecular Weight	221.30 g/mol
Synonyms	(S)-3-Amino-3-phenylpropanoic acid tert-butyl ester; (S)-tert-Butyl 3-amino-3-phenylpropanoate; (S)-β-Phenyl-β-alanine tert-butyl ester; (S)-3-Phenyl-β-alanine tert-butyl ester; H-β-Phe-OtBu; (S)-3-Amino-3-phenylpropionic acid t-butyl ester; (S)-3-Phenylalanine tert-butyl ester hydrochloride (salt form); (S)-3-Phe-OtBu
EINECS	Contact for details

Quality Control

Our (S)-3-Phenylalanine T-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.