Description

2-Acetylaminofluorene-n-Sulfate is a key sulfated derivative of the aromatic amine 2-acetylaminofluorene, a compound of significant interest in biochemical and toxicological research. This sulfate ester is primarily valued for its role as a critical metabolite and reference standard in studies investigating metabolic activation pathways, DNA adduct formation, and chemical carcinogenesis. It is an essential material for research laboratories, pharmaceutical R&D departments, and toxicology testing facilities focused on understanding the mechanisms of action of aromatic amines and developing related safety assessments.

Application

• Biochemical Research Standard: Used as a high-purity reference standard in analytical chemistry for calibrating instruments and validating methods in metabolite detection.
• Toxicology & Carcinogenesis Studies: Serves as a crucial intermediate in research models studying the metabolic activation of pro-carcinogens and the subsequent formation of DNA adducts.
• Pharmaceutical Metabolism Research: Employed in investigative studies to understand the Phase II sulfation pathways of drug candidates and related xenobiotics.
• Academic & Institutional Research: Utilized in university and government laboratories for fundamental research in chemical biology and molecular toxicology.
• Analytical Method Development: Acts as a key analyte for developing and optimizing advanced chromatographic (HPLC, LC-MS) techniques for sulfate-conjugated metabolites.

Basic Information

Product Name	2-Acetylaminofluorene-n-Sulfate
CAS No.	16808-85-8
Molecular Formula	C15H13NO4S
Molecular Weight	303.33 g/mol
Synonyms	2-AAF-N-Sulfate; N-Sulfooxy-2-acetylaminofluorene; 2-Acetamidofluorene N-Sulfate; 2-Acetylaminofluorene Sulfate Ester; 2-AAF Sulfate; N-(9H-Fluoren-2-yl)acetamide Sulfate; 2-Acetamidofluorene Sulfate; 2-AAF-SO4
EINECS	Contact for details

Quality Control

Our 2-Acetylaminofluorene-n-Sulfate is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including identity confirmation by spectroscopic methods and purity assessment by HPLC. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.