Description

Leu-Leu Methyl Ester Hydrobromide is a protected dipeptide derivative, specifically the hydrobromide salt of the methyl ester of L-leucyl-L-leucine. This compound serves as a crucial building block in organic synthesis and peptide chemistry, offering a protected N-terminus and activated C-terminus for controlled chain elongation. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers engaged in the development of peptide-based therapeutics, diagnostic agents, and biochemical tools.

Application

• Peptide Synthesis Intermediate: A key protected fragment for the solid-phase or solution-phase synthesis of longer, more complex peptide sequences containing leucine residues.
• Pharmaceutical Research: Used in the research and development of novel peptide drugs, prodrugs, and bioactive compounds targeting various therapeutic areas.
• Biochemical Tool Development: Employed in the creation of enzyme substrates, inhibitors, or affinity ligands for proteomics and biochemical studies.
• Fine Chemical Production: Acts as a specialized intermediate in the multi-step synthesis of high-value, non-peptide organic molecules for agrochemical or material science applications.
• Academic & Industrial R&D: Serves as a standard or starting material in laboratories focused on medicinal chemistry, organic methodology, and chemical biology.

Basic Information

Product Name	Leu-Leu Methyl Ester Hydrobromide
CAS No.	16689-14-8
Molecular Formula	C14H27N2O3 • HBr
Molecular Weight	353.29 g/mol
Synonyms	L-Leucyl-L-leucine methyl ester hydrobromide; Methyl L-leucyl-L-leucinate hydrobromide; H-Leu-Leu-OMe • HBr; Leu-Leu-OMe HBr; (2S)-2-[[(2S)-2-Amino-4-methylpentanoyl]amino]-4-methylpentanoic acid methyl ester hydrobromide; LL-OMe • HBr; N-(L-Leucyl)-L-leucine methyl ester hydrobromide
EINECS	Contact for details

Quality Control

Our Leu-Leu Methyl Ester Hydrobromide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric integrity, and identity confirmation via spectroscopic methods. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.