Description

Z-Tyr-Nhnh2 CAS NO 16679-95-1 is a specialized protected tyrosine derivative, specifically the hydrazide of N-carbobenzoxy-L-tyrosine. This compound is a crucial building block in advanced organic synthesis, particularly in peptide chemistry, where it serves as a key intermediate for the controlled introduction of tyrosine residues. It is essential for research and development chemists in the pharmaceutical and biotechnology sectors who require high-purity, well-characterized precursors for synthesizing novel peptides, peptidomimetics, and other bioactive molecules. The product's defined structure and purity are critical for ensuring reproducibility and success in complex synthetic pathways.

Application

• Peptide Synthesis: A fundamental building block (amino acid derivative) for the solid-phase and solution-phase synthesis of custom peptides and peptide libraries.
• Pharmaceutical Intermediates: Serves as a key precursor in the research and development of potential therapeutic agents, including hormone analogs and enzyme inhibitors.
• Bioconjugation Chemistry: Used in the preparation of protein conjugates, antibody-drug conjugates (ADCs), and other biomolecule labeling strategies via its reactive hydrazide group.
• Chemical Biology Research: Employed in the study of protein-protein interactions, signal transduction pathways, and the development of biochemical probes.
• Material Science: Potential use in the synthesis of specialty polymers and smart materials that incorporate bioactive peptide sequences.

Basic Information

Product Name	Z-Tyr-Nhnh2 CAS NO 16679-95-1
CAS No.	16679-95-1
Molecular Formula	C17H18N2O5
Molecular Weight	330.34 g/mol
Synonyms	N-Carbobenzoxy-L-tyrosine hydrazide; Z-L-Tyrosine hydrazide; Z-Tyr-NHNH2; CBZ-L-Tyrosine hydrazide; Nα-Benzyloxycarbonyl-L-tyrosine hydrazide; (2S)-2-[[(Benzyloxy)carbonyl]amino]-3-(4-hydroxyphenyl)propanehydrazide; Z-Tyrosine-NHNH2; L-Tyrosine, N-[(phenylmethoxy)carbonyl]-, hydrazide
EINECS	Contact for details

Quality Control

Our Z-Tyr-Nhnh2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific optical rotation measurement to ensure identity and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles and rigorous quality control ensures a reliable supply of high-purity material for your critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Optical Rotation	-10.0° to -12.0° (c=1 in DMF)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.