Description

L-Lysine, N2-Acetyl-N6-[(1,1-Dimethylethoxy)Carbonyl]-, Methyl Ester is a protected derivative of the essential amino acid L-Lysine, featuring orthogonal protecting groups on its alpha and epsilon amines. This compound is a critical building block in advanced organic synthesis, particularly for the production of peptides and complex biomolecules where selective deprotection is required. It is essential for researchers and manufacturers in pharmaceutical development, biotechnology, and fine chemical synthesis who require high-purity, well-characterized intermediates for reliable and scalable processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of peptide-based drugs, APIs (Active Pharmaceutical Ingredients), and complex therapeutic molecules.
• Peptide Synthesis: Serves as a protected lysine residue in Solid-Phase Peptide Synthesis (SPPS) and solution-phase peptide chemistry, enabling the controlled elongation of peptide chains.
• Bioconjugation & Labeling: Used in the preparation of modified peptides and proteins for research, diagnostics, and targeted drug delivery systems.
• Chemical Biology Research: Employed as a tool compound for studying protein-protein interactions, enzyme mechanisms, and for the development of novel biochemical probes.
• Fine Chemical Synthesis: Acts as a chiral building block for the asymmetric synthesis of non-peptidic compounds with biological activity.

Basic Information

Item	Detail
Product Name	L-Lysine, N2-Acetyl-N6-[(1,1-Dimethylethoxy)Carbonyl]-, Methyl Ester
CAS No.	16679-49-5
Molecular Formula	C14H26N2O5
Molecular Weight	302.37 g/mol
Synonyms	Nα-Acetyl-Nε-Boc-L-lysine methyl ester; Nα-Acetyl-Nε-(tert-butoxycarbonyl)-L-lysine methyl ester; Boc-Lys(Ac)-OMe; Methyl N2-acetyl-N6-(tert-butoxycarbonyl)-L-lysinate; (S)-Methyl 2-acetamido-6-((tert-butoxycarbonyl)amino)hexanoate; Ac-Lys(Boc)-OMe; Protected L-Lysine methyl ester
EINECS	Contact for details

Quality Control

Our L-Lysine derivative is manufactured under strict quality systems to ensure batch-to-batch consistency and high chemical purity, suitable for demanding synthetic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to industry best practices and can provide material tailored to specific research or cGMP requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]D20	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.