Description

Z-Tyr(Bzl)-OH is a protected tyrosine derivative, specifically the benzyl (Bzl) ether of N-carbobenzoxy (Z) tyrosine. This compound is a critical building block in solid-phase peptide synthesis (SPPS), where it provides orthogonal protection for the tyrosine side chain hydroxyl group. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require high-purity, reliable intermediates for constructing complex peptides and peptidomimetics.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the controlled, sequential assembly of peptide chains, particularly where tyrosine residues are required.
• Pharmaceutical Intermediate: Used in the research and development of therapeutic peptides, including hormone analogs, enzyme inhibitors, and antimicrobial peptides.
• Bioconjugation & Labeling: Serves as a precursor for introducing tyrosine-based linkers or tags into biomolecules for diagnostic or targeting applications.
• Chemical Biology Research: Employed in the study of protein-protein interactions, signal transduction pathways, and the development of novel bioactive compounds.
• Custom Peptide Service: A fundamental raw material for contract research organizations (CROs) and CDMOs offering bespoke peptide manufacturing services.

Basic Information

Product Name	Z-Tyr(Bzl)-OH
CAS No.	16677-29-5
Molecular Formula	C24H23NO5
Molecular Weight	405.44 g/mol
Synonyms	N-Carbobenzoxy-O-benzyl-L-tyrosine; Z-O-Benzyl-L-tyrosine; (2S)-2-[[(Benzyloxy)carbonyl]amino]-3-[4-(phenylmethoxy)phenyl]propanoic acid; Z-Tyr(OBzl)-OH; Z-L-Tyrosine benzyl ester precursor; Cbz-Tyr(Bzl)-OH; N-Cbz-O-benzyl-L-tyrosine; Benzyl N-[(benzyloxy)carbonyl]-L-tyrosinate acid form
EINECS	Contact for details

Quality Control

Our Z-Tyr(Bzl)-OH is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment to ensure it meets the stringent requirements for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.