Description

(+)-Normetazocine n-Demethylated Analog is a high-purity synthetic organic compound of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the study of opioid receptor pharmacology and the synthesis of novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in neuroscience, medicinal chemistry, and analgesic drug discovery programs.

Application

• Pharmaceutical Research Intermediate: A key building block in the synthesis of novel opioid receptor ligands and potential analgesic compounds.
• Reference Standard: Used as a high-purity analytical standard in method development and quality control for related pharmaceutical actives.
• Medicinal Chemistry Studies: Employed in structure-activity relationship (SAR) studies to understand the pharmacophore of benzomorphan-based compounds.
• Neuroscience Research: Utilized in biochemical and pharmacological assays to investigate opioid receptor subtypes and signaling pathways.
• Process Development: Serves as a critical material in scaling up synthetic routes for potential active pharmaceutical ingredients (APIs).
• Metabolite Synthesis: Used in the preparation of drug metabolites for identification and toxicological studies.

Basic Information

Product Name	(+)-Normetazocine n-Demethylated Analog
CAS No.	16670-83-0
Molecular Formula	C15H21NO
Molecular Weight	231.33 g/mol
Synonyms	(+)-N-Nornormetazocine; (+)-N-Nor-5,9α-dimethyl-2'-hydroxy-6,7-benzomorphan; 1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-phenethyl-2,6-methano-3-benzazocin-8-ol; 2'-Hydroxy-5,9α-dimethyl-2-phenethyl-6,7-benzomorphan; Desmethylnormetazocine; Nor-5,9α-dimethyl-2'-hydroxy-6,7-benzomorphan
EINECS	Contact for details

Quality Control

Our (+)-Normetazocine n-Demethylated Analog is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods (IR, NMR, MS), and residual solvent analysis to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.