Description

2-Fluoroadamantane is a high-value fluorinated derivative of the adamantane cage structure, prized for its unique combination of lipophilicity, metabolic stability, and steric bulk. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in medicinal chemistry and materials science. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and specialty polymer industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated drug candidates, particularly in central nervous system (CNS) and antiviral research, leveraging its ability to modulate bioavailability and metabolic stability.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and as a bioisostere to introduce fluorine atoms, enhancing the potency and pharmacokinetic properties of lead compounds.
• Agrochemical Synthesis: Intermediate in the development of advanced, fluorinated pesticides and herbicides, where the adamantane core contributes to weather resistance and biological activity.
• Material Science Precursor: Serves as a monomer or additive in the synthesis of specialty polymers, coatings, and liquid crystals, imparting thermal stability and unique electronic properties.
• Organic Synthesis & Catalysis: Valuable fluorinated scaffold for exploring novel organic reactions and as a ligand or component in catalytic systems.
• Research & Development: Essential reference standard and starting material in academic and industrial R&D laboratories for exploring fluorocarbon chemistry and new applications.

Basic Information

Item	Detail
Product Name	2-Fluoroadamantane
CAS No.	16668-83-0
Molecular Formula	C10H15F
Molecular Weight	154.22 g/mol
Synonyms	2-Fluorotricyclo[3.3.1.13,7]decane; Fluoroadamantane; 2-Fluoro-adamantane; 2-Fluoroadamantane; Adamantane, 2-fluoro-; 2-Fluorotricyclodecane
EINECS	Contact for details

Quality Control

Our 2-Fluoroadamantane is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.