Description

(2R)-2-(Acetylamino)-4-Methylpentanamide is a chiral, non-proteinogenic amino acid derivative characterized by its specific stereochemistry at the 2-position. This compound matters as a high-purity building block for the synthesis of complex peptides and pharmaceutical intermediates, offering precise control over molecular structure. It is needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for applications in drug discovery and development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for peptide-based therapeutics.
• Peptide Synthesis: Used as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis to introduce specific structural motifs.
• Biochemical Research: Serves as a standard or reagent in enzymatic studies and metabolic pathway investigations.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective organic synthesis.
• Proteomics & Diagnostics: Potential use in the development of specialized reagents for protein analysis and diagnostic assays.

Basic Information

Product Name	(2R)-2-(Acetylamino)-4-Methylpentanamide
CAS No.	16624-68-3
Molecular Formula	C8H16N2O2
Molecular Weight	172.23 g/mol
Synonyms	N-Acetyl-D-leucinamide; D-N-Acetylleucinamide; (R)-2-Acetamido-4-methylpentanamide; (2R)-2-Acetamido-4-methylpentanamide; Ac-D-Leu-NH2; N-Acetyl-D-leucine amide; D-Leucine, N-acetyl-, amide; N-Acetyl-D-leucineamide
EINECS	Contact for details

Quality Control

Our (2R)-2-(Acetylamino)-4-Methylpentanamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as chiral purity, assay, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.