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[Hydroxy-[Hydroxy-[[(2R,3S,5R)-3-Hydroxy-5-(6-Oxo-3H-Purin-9-Yl)Oxolan-2-Yl]Methoxy]Phosphoryl]Oxy-Phosphoryl]Oxyphosphonic Acid CAS NO 16595-02-1


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CAS No.:16595-02-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Hydroxy-[Hydroxy-[[(2R,3S,5R)-3-Hydroxy-5-(6-Oxo-3H-Purin-9-Yl)Oxolan-2-Yl]Methoxy]Phosphoryl]Oxy-Phosphoryl]Oxyphosphonic Acid is a high-purity nucleotide derivative, a key intermediate in the synthesis of complex biomolecules. This compound is critical for research and development in life sciences, offering a reliable building block for advanced biochemical applications. It is essential for pharmaceutical R&D, academic research, and the production of specialized nucleotide-based reagents.

Application

  • Pharmaceutical Intermediate: A crucial building block in the synthesis of novel antiviral and anticancer nucleotide analogs.
  • Biochemical Research: Used in enzymatic studies, metabolic pathway analysis, and as a substrate or inhibitor for nucleotide-processing enzymes.
  • Proteomics & Genomics: Serves as a precursor for labeled nucleotides used in sequencing, PCR, and other molecular biology techniques.
  • Diagnostic Reagent Manufacturing: Employed in the production of high-sensitivity assay components for clinical diagnostics.
  • Academic & Institutional Research: A valuable tool for universities and research institutes studying nucleic acid chemistry and biology.
  • Precursor for Prodrugs: Utilized in the development of nucleotide prodrugs designed for improved bioavailability and targeted delivery.

Basic Information

Product Name Hydroxy-[Hydroxy-[[(2R,3S,5R)-3-Hydroxy-5-(6-Oxo-3H-Purin-9-Yl)Oxolan-2-Yl]Methoxy]Phosphoryl]Oxy-Phosphoryl]Oxyphosphonic Acid
CAS No. 16595-02-1
Molecular Formula C10H15N5O13P3
Molecular Weight 506.16 g/mol
Synonyms 9-[(2R,3S,5R)-3-Hydroxy-5-[[hydroxy(phosphonooxy)phosphoryl]oxymethyl]oxolan-2-yl]-3H-purin-6-one; Adenosine 5'-(tetrahydrogen triphosphate); Adenosine triphosphoric acid; ATP (free acid); Adenosine 5'-triphosphate; 5'-ATP; Adenylpyrophosphoric acid; 9-β-D-Ribofuranosyladenine 5'-(tetrahydrogen triphosphate)
EINECS Contact for details

Quality Control

Our Hydroxy-[Hydroxy-[[(2R,3S,5R)-3-Hydroxy-5-(6-Oxo-3H-Purin-9-Yl)Oxolan-2-Yl]Methoxy]Phosphoryl]Oxy-Phosphoryl]Oxyphosphonic Acid is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical applications. Certificates of Analysis (COA) documenting purity, identity, and impurity profiles are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term stability, store desiccated under inert atmosphere. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms
Identification (NMR) Conforms
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Heavy Metals ≤ 20 ppm
Residual Solvents (GC) Meets ICH guidelines
Biological Activity (Enzymatic Assay) Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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