Description

4-Phenyl-1-Butyne is a versatile alkyne-substituted aromatic compound, serving as a crucial building block in advanced organic synthesis. Its unique structure, featuring a terminal alkyne group attached to a phenylbutyl chain, makes it a valuable intermediate for constructing complex molecular architectures. This compound is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for applications such as cross-coupling reactions and the synthesis of bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers and advanced organic materials.
• Cross-Coupling Reactions: An essential reagent in Sonogashira, Heck, and other palladium-catalyzed coupling reactions to form carbon-carbon bonds.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A fundamental tool in academic and industrial R&D for exploring new synthetic pathways and compound libraries.

Basic Information

Product Name	4-Phenyl-1-Butyne
CAS No.	16520-62-0
Molecular Formula	C10H10
Molecular Weight	130.19 g/mol
Synonyms	1-Butyne, 4-phenyl-; 4-Phenylbut-1-yne; (3-Butyn-1-yl)benzene; 4-Phenylbutyne; Phenylbutyne; 16520-62-0; But-1-yn-4-ylbenzene
EINECS	Contact for details

Quality Control

Our 4-Phenyl-1-Butyne is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for research and industrial-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and open flame. Due to its highly volatile nature, the container must be kept tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.