Description

2-Amino-5-Trifluoromethylbenzamide is a high-value trifluoromethylated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino and an amide group adjacent to a trifluoromethyl substituent, enables precise molecular modifications essential for developing novel compounds. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the trifluoromethyl group improves biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, contributing to materials with specific optical or electronic properties.
• Organic Light-Emitting Diode (OLED) Materials: Employed in the synthesis of electron-transport or host materials for next-generation display technologies.
• Fluorinated Dye & Pigment Development: Acts as a starting material for creating dyes with superior light-fastness and chemical resistance.
• Chemical Research & Custom Synthesis: A versatile reagent for academic and industrial research focused on fluorine chemistry and heterocyclic compound formation.

Basic Information

Product Name	2-Amino-5-Trifluoromethylbenzamide
CAS No.	16499-54-0
Molecular Formula	C8H7F3N2O
Molecular Weight	204.15 g/mol
Synonyms	5-(Trifluoromethyl)anthranilamide; 2-Amino-α,α,α-trifluoro-m-toluamide; 2-Amino-5-(trifluoromethyl)benzamide; 2-Amino-α,α,α-trifluoro-m-toluamide; m-(Aminocarbonyl)-α,α,α-trifluoro-o-toluidine; 5-Trifluoromethyl Anthranilamide; 2-Carbamoyl-4-(trifluoromethyl)aniline; Benzamide, 2-amino-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Trifluoromethylbenzamide is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. For customers with specific regulatory needs, we can support documentation for GMP or ISO-guided applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if opened for prolonged periods. Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.