Description

L-Serine Hydrochloride is the hydrochloride salt form of the essential amino acid L-Serine, offering enhanced stability and solubility for precise formulation needs. This high-purity chiral building block is critical for synthesizing bioactive peptides, pharmaceutical intermediates, and advanced cell culture media. It serves as a vital raw material for manufacturers in the pharmaceutical, biotechnology, and nutraceutical industries requiring consistent, high-quality amino acid derivatives.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of various active pharmaceutical ingredients (APIs) and therapeutic peptides.
• Cell Culture & Fermentation: Component of specialized cell culture media and fermentation broths used in biopharmaceutical production and vaccine development.
• Biochemical Research: Essential reagent in proteomics research, enzyme studies, and as a standard in analytical chemistry.
• Nutraceutical & Cosmetic Formulations: Used in advanced dietary supplements and skincare products for its role in collagen synthesis and cellular metabolism.
• Chemical Synthesis: Chiral synthon in asymmetric synthesis and for protecting group strategies in organic chemistry.

Basic Information

Product Name	L-Serine Hydrochloride
CAS No.	16428-75-4
Molecular Formula	C3H8ClNO3
Molecular Weight	157.55 g/mol
Synonyms	(S)-2-Amino-3-hydroxypropanoic acid hydrochloride; L-2-Amino-3-hydroxypropionic acid hydrochloride; Serine HCl; (S)-Serine hydrochloride; L-Serine HCl; H-Ser-OH·HCl; L-α-Amino-β-hydroxypropionic acid hydrochloride
EINECS	240-458-5

Quality Control

Our L-Serine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, specific rotation for chiral identity, and tests for residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with cGMP and relevant pharmacopeial guidelines (USP/EP) where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent caking and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥98.5%
Specific Rotation [α]20/D	+14.5° to +16.5° (c=1 in H2O)
Loss on Drying	≤0.5%
Residue on Ignition (Sulfated Ash)	≤0.1%
Heavy Metals (as Pb)	≤10 ppm
Chloride Content (Titration)	21.5% - 22.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.