Description

(R)-Dimethyl 2-Aminopentanedioate is a high-purity chiral building block and protected amino acid derivative. This compound is a critical intermediate in the synthesis of complex pharmaceutical molecules, particularly those targeting neurological and metabolic disorders. It is essential for research and production in the pharmaceutical, biotechnology, and fine chemical industries where precise stereochemistry and high purity are non-negotiable.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the production of active pharmaceutical ingredients (APIs), especially in neurology and metabolic disease research.
• Peptide Synthesis: Serves as a protected glutamic acid derivative in solid-phase and solution-phase peptide synthesis.
• Asymmetric Synthesis: Used as a starting material or auxiliary in catalytic asymmetric reactions to construct complex molecular architectures.
• Bioconjugation & Probe Development: Utilized in the development of biochemical probes and labeled compounds for diagnostic and research applications.
• Academic & Industrial R&D: Fundamental building block in medicinal chemistry and process development laboratories.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, flavors, and fragrances requiring specific enantiomeric purity.

Basic Information

Product Name	(R)-Dimethyl 2-Aminopentanedioate
CAS No.	16422-27-8
Molecular Formula	C7H13NO4
Molecular Weight	175.18 g/mol
Synonyms	(R)-2-Aminopentanedioic Acid Dimethyl Ester; D-Dimethyl Aminoglutarate; (R)-Dimethyl Aminoglutarate; (R)-Dimethyl 2-Aminoglutarate; (2R)-2-Aminopentanedioic Acid Dimethyl Ester; (R)-1,5-Dimethyl 2-Aminopentanedioate; D-Glutamic Acid Dimethyl Ester; (R)-Glutamic Acid Dimethyl Ester
EINECS	Contact for details

Quality Control

Our (R)-Dimethyl 2-Aminopentanedioate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.