Description

Proline, 2-Methyl-, Ethyl Ester, Dl- (8Ci) is a chiral, non-proteinogenic amino acid derivative, specifically an ethyl ester of 2-methylproline. This compound matters as a versatile and high-purity building block and intermediate for advanced organic synthesis, enabling the creation of complex molecules with precise stereochemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in peptidomimetic drug discovery, the development of enzyme inhibitors, and the synthesis of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for peptidomimetics and protease inhibitors.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to introduce constrained proline analogs, modifying peptide backbone conformation and stability.
• Asymmetric Synthesis: Serves as a precursor or auxiliary in catalytic asymmetric reactions to construct stereogenic centers.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies to probe the activity and mechanism of proline-specific enzymes.
• Agrochemical Development: Potential intermediate for synthesizing novel chiral herbicides or plant growth regulators.
• Material Science: Can be incorporated into specialty polymers or coatings to impart specific chiral or structural properties.

Basic Information

Product Name	Proline, 2-Methyl-, Ethyl Ester, Dl- (8Ci)
CAS No.	16277-07-9
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	DL-2-Methylproline ethyl ester; Ethyl DL-2-methylprolinate; (±)-2-Methylproline ethyl ester; Ethyl 2-methylpyrrolidine-2-carboxylate; 2-Pyrrolidinecarboxylic acid, 2-methyl-, ethyl ester, (±)-; 2-Methylproline ethyl ester; Proline, 2-methyl-, ethyl ester, DL-; (±)-Ethyl 2-methylprolinate
EINECS	Contact for details

Quality Control

Our Proline, 2-Methyl-, Ethyl Ester, Dl- (8Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (GC/HPLC)	DL-mixture (racemic)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.