Description

Boc-Ile-Gly-Oh is a protected dipeptide building block, specifically N-(tert-Butoxycarbonyl)-Isoleucyl-Glycine. This compound is a critical intermediate in the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require high-purity, reliable starting materials for developing therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel therapeutic peptides targeting metabolic disorders, cancer, and infectious diseases.
• Peptide Research: Used in academic and industrial R&D for constructing peptide libraries and studying structure-activity relationships (SAR).
• Bioconjugation: Serves as a spacer or linker molecule in the development of peptide-drug conjugates (PDCs) and other bioconjugates.
• Protease Substrate Synthesis: Employed in the preparation of specific substrates for enzyme activity assays and inhibitor studies.
• Custom Peptide Service: A fundamental reagent for contract research and manufacturing organizations (CROs/CMOs) offering custom peptide synthesis services.
• Biochemical Tool Development: Integral for creating labeled peptides, affinity probes, and other tools used in molecular biology and diagnostics.

Basic Information

Product Name	Boc-Ile-Gly-Oh
CAS No.	16257-05-9
Molecular Formula	C13H24N2O5
Molecular Weight	288.34 g/mol
Synonyms	N-(tert-Butoxycarbonyl)isoleucylglycine; Boc-Isoleucyl-Glycine; Boc-Ile-Gly-OH; BOC-Ile-Gly; N-Boc-Ile-Gly-OH; (2S,3S)-2-[[(2-tert-Butoxycarbonylamino)-3-methylpentanoyl]amino]acetic acid; tert-Butyloxycarbonylisoleucylglycine; Nα-Boc-Isoleucyl-Glycine
EINECS	Contact for details

Quality Control

Our Boc-Ile-Gly-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR). We provide comprehensive Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or cGMP-grade requirements. Our quality commitment supports your need for reliable and consistent peptide synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	-20° to -25° (c=1 in DMF)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.