Description

3,4β-Dimethyl-5α-Phenyloxazolidine-2-One is a specialized heterocyclic organic compound featuring a phenyl-substituted oxazolidinone core. This structure makes it a valuable chiral building block and intermediate in advanced organic synthesis, particularly for the development of pharmaceuticals and agrochemicals. It is sought after by research institutions and industrial manufacturers engaged in the production of active pharmaceutical ingredients (APIs), fine chemicals, and novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of complex drug molecules, including potential central nervous system (CNS) agents and antimicrobials.
• Agrochemical Research: Serves as a precursor for developing novel herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Fine Chemical Synthesis: Used in constructing complex molecular architectures for specialty chemicals, dyes, and functional materials.
• Asymmetric Catalysis: Employed as a ligand or auxiliary in catalytic reactions to induce chirality and control stereoselectivity.
• Academic & R&D: A critical reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	3,4β-Dimethyl-5α-Phenyloxazolidine-2-One
CAS No.	16251-47-1
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	5α-Phenyl-3,4β-dimethyloxazolidin-2-one; 3,4-Dimethyl-5-phenyl-2-oxazolidinone; (4R,5S)-4,5-Dimethyl-3-phenyl-2-oxazolidinone; (4S,5R)-4,5-Dimethyl-3-phenyl-2-oxazolidinone; Evans Auxiliary derivative; Phenyloxazolidinone chiral auxiliary; 2-Oxazolidinone, 3,4-dimethyl-5-phenyl-; Contact for additional trade names.
EINECS	Contact for details

Quality Control

We supply 3,4β-Dimethyl-5α-Phenyloxazolidine-2-One in high-purity grades suitable for research and industrial synthesis. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles are available upon request. We adhere to cGMP principles where applicable to ensure batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (ee)	≥ 99.0% (Specific enantiomer available)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.