Description

Ethanone, 1-(2,4-Dimethylphenyl)-2,2,2-Trifluoro- (9Ci) is a specialized trifluoromethyl ketone derivative, a high-value intermediate prized for its unique structural motif that combines aromatic and fluorinated components. This compound is critical for driving innovation in advanced material science and pharmaceutical research, where its properties enable the synthesis of novel, performance-enhancing molecules. It is primarily sought by R&D chemists and process development teams in the agrochemical, pharmaceutical, and specialty chemical industries for constructing complex target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring the trifluoromethyl group for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Liquid Crystal & OLED Material Research: Acts as a precursor in the development of fluorinated organic compounds for electronic displays and lighting applications.
• Advanced Polymer Chemistry: Employed to introduce fluorinated segments into polymer chains, modifying surface properties, chemical resistance, and thermal stability.
• Organic Synthesis & Catalysis: A versatile reagent in academic and industrial laboratories for constructing complex organic frameworks via reactions like nucleophilic addition or as a ligand precursor.
• Fluorine Chemistry Research: Essential for studying structure-activity relationships (SAR) and developing new fluorination methodologies.

Basic Information

Product Name	Ethanone, 1-(2,4-Dimethylphenyl)-2,2,2-Trifluoro- (9Ci)
CAS No.	16184-87-5
Molecular Formula	C10H9F3O
Molecular Weight	202.17 g/mol
Synonyms	2',4'-Dimethyl-2,2,2-trifluoroacetophenone; 1-(2,4-Dimethylphenyl)-2,2,2-trifluoroethanone; 2,4-Dimethyl-α,α,α-trifluoroacetophenone; 2,2,2-Trifluoro-1-(2,4-dimethylphenyl)ethanone; α,α,α-Trifluoro-2',4'-dimethylacetophenone; 2,4-Dimethyltrifluoroacetophenone; TFAP derivative
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our fine chemical intermediates. Production batches are analyzed using advanced techniques including GC, HPLC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment. Our quality system is designed to support cGMP and ISO standards for traceability and reliability, meeting the rigorous demands of global pharmaceutical and agrochemical supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Purity (GC Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.