Description

Pyrimidine, 4-Amino-2-(Fluoromethyl)- (8Ci) is a specialized fluorinated pyrimidine derivative, a high-value building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of a fluoromethyl group can significantly alter biological activity and metabolic stability. It is primarily needed by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fine chemical sectors focused on creating next-generation fluorinated compounds.

Application

• As a critical synthetic intermediate in the research and development of novel pharmaceutical agents, particularly anticancer and antiviral drugs.
• In the synthesis of advanced agrochemicals, such as herbicides and fungicides, where fluorination enhances efficacy and environmental profile.
• For the preparation of custom fluorinated ligands and catalysts used in asymmetric synthesis and material science.
• As a key scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• In the development of molecular probes and diagnostic agents for biochemical research and imaging.
• For the production of specialty fine chemicals and high-value additives with specific performance characteristics.

Basic Information

Product Name	Pyrimidine, 4-Amino-2-(Fluoromethyl)- (8Ci)
CAS No.	16097-51-1
Molecular Formula	C5H6FN3
Molecular Weight	127.12 g/mol
Synonyms	2-(Fluoromethyl)-4-aminopyrimidine; 4-Amino-2-(fluoromethyl)pyrimidine; 4-Amino-2-fluoromethylpyrimidine; 2-Fluoromethyl-4-aminopyrimidine; 4-Pyrimidinamine, 2-(fluoromethyl)-; 4-Amino-2-(fluoromethyl)pyrimidine (8CI); 2-(Fluoromethyl)pyrimidin-4-amine
EINECS	Contact for details

Quality Control

Our Pyrimidine, 4-Amino-2-(Fluoromethyl)- (8Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our commitment to cGMP and ISO 9001 standards ensures traceability, consistency, and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.