Description

L-Proline β-Naphthylamide Hydrochloride is a specialized biochemical reagent, primarily used as a chromogenic substrate for the detection and quantification of proline-specific peptidase and aminopeptidase P activity. This compound is critical for researchers and manufacturers requiring precise enzymatic analysis in diagnostic and biochemical research applications. It serves as an essential tool for pharmaceutical R&D, clinical diagnostics, and academic research in enzymology and proteomics.

Application

• Enzymatic Substrate: A key chromogenic substrate for the spectrophotometric assay of proline-specific endopeptidases and aminopeptidase P.
• Diagnostic Reagent Manufacturing: Used in the formulation of diagnostic kits for detecting specific enzyme activities related to various physiological and pathological conditions.
• Biochemical Research: Essential for studying enzyme kinetics, inhibitor screening, and characterizing protease activity in research laboratories.
• Pharmaceutical Development: Employed in drug discovery programs targeting proline-specific enzymes, which are implicated in several disease pathways.
• Quality Control in Biotechnology: Used as a reference standard in the quality control of enzyme preparations and related bioproducts.
• Microbiology Studies: Applied in research to investigate microbial proteases that cleave at proline residues.

Basic Information

Product Name	L-Proline β-Naphthylamide Hydrochloride
CAS No.	16037-15-3
Molecular Formula	C₁₅H₁₇ClN₂O
Molecular Weight	276.76 g/mol
Synonyms	L-Proline 2-Naphthylamide Hydrochloride; Proline-β-naphthylamide HCl; N-α-(2-Naphthyl)-L-prolinamide Hydrochloride; L-Pro-2-NA HCl; Proline β-NA HCl; Proline-β-NA Hydrochloride; (S)-1-(Naphthalen-2-ylcarbamoyl)pyrrolidine-2-carboxylic acid hydrochloride
EINECS	Contact for details

Quality Control

Our L-Proline β-Naphthylamide Hydrochloride is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency suitable for sensitive research and diagnostic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for biochemical reagents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. Handle with care to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.