Description

(C20:0) Coenzyme A CAS NO 15895-27-9 is a high-purity, long-chain fatty acyl-CoA derivative, specifically the arachidoyl-CoA ester, which serves as a critical metabolic intermediate. This compound is essential for researchers and manufacturers studying or manipulating lipid metabolism, fatty acid elongation, and enzyme specificity. It is primarily utilized in biochemical research, pharmaceutical development, and as a reference standard in analytical laboratories for lipidomics and metabolic pathway analysis.

Application

• Biochemical Research: As a substrate for studying enzymes like acyl-CoA synthetases, elongases, and desaturases in fatty acid metabolism pathways.
• Pharmaceutical Development: Used in target identification and validation for metabolic disorders, such as those related to very long-chain fatty acid synthesis.
• Diagnostic Reagent Manufacturing: A key component in enzymatic assay kits designed to measure specific metabolic enzyme activities in clinical and research settings.
• Lipidomics & Metabolomics: Serves as a critical internal or external standard for the accurate quantification of acyl-CoA species via LC-MS/MS and other analytical techniques.
• Enzyme Kinetics & Inhibition Studies: Provides a defined substrate for determining kinetic parameters (Km, Vmax) and screening for potential inhibitors.
• Cell Culture & In Vitro Studies: Used to supplement media in studies investigating the effects of specific fatty acyl-CoAs on cell signaling, membrane composition, and energy homeostasis.

Basic Information

Product Name	(C20:0) Coenzyme A
CAS No.	15895-27-9
Molecular Formula	C₄₁H₇₂N₇O₁₇P₃S
Molecular Weight	1044.02 g/mol
Synonyms	Arachidoyl-Coenzyme A; Arachidoyl-CoA; Eicosanoyl-Coenzyme A; Eicosanoyl-CoA; CoA(20:0); S-Arachidoylcoenzyme A; 3'-Phosphoadenosine 5'-(3-[(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-{[3-oxo-3-({2-[(1-oxoicosyl)sulfanyl]ethyl})amino)propyl]amino}butyl] dihydrogen diphosphate); Arachidic acid-CoA
EINECS	Contact for details

Quality Control

Our (C20:0) Coenzyme A is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via mass spectrometry, to ensure it meets the high standards required for research and diagnostic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay results, and stability data.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and easily oxidized; therefore, it must be handled under anhydrous conditions and sealed under vacuum or nitrogen after each use to ensure long-term stability. Allow the vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (Enzymatic)	≥ 90%
Water Content (KF)	≤ 5%
Solubility	Soluble in water or appropriate buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.