Description

Cyclopropylalanine is a non-proteinogenic amino acid featuring a cyclopropyl side chain, a structural motif of significant interest in medicinal chemistry. This unique conformationally restricted building block is crucial for modulating the pharmacokinetic and pharmacodynamic properties of peptide-based therapeutics. It serves as a key chiral intermediate for researchers and manufacturers in the pharmaceutical and biotechnology sectors, enabling the development of novel drug candidates with enhanced metabolic stability and receptor selectivity.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the synthesis of protease inhibitors, enzyme inhibitors, and other bioactive peptides.
• Peptide Drug Discovery: Used to incorporate conformational constraints into peptide backbones, improving stability against enzymatic degradation and enhancing binding affinity.
• Chemical Biology Research: Employed as a tool compound for studying enzyme-substrate interactions and for the development of activity-based probes.
• Agrochemical Synthesis: Serves as a building block for developing novel peptides with potential herbicidal or insecticidal activity.
• Material Science: Potential monomer for the synthesis of specialized polyamides or peptide-based polymers with unique properties.

Basic Information

Product Name	Cyclopropylalanine
CAS No.	15785-52-1
Molecular Formula	C₆H₁₁NO₂
Molecular Weight	129.16 g/mol
Synonyms	(S)-2-Amino-3-cyclopropylpropanoic acid; (S)-Cyclopropylalanine; (S)-2-Amino-3-cyclopropylpropionic acid; L-Cyclopropylalanine; Cyclopropanealanine; (S)-3-Cyclopropylalanine; 3-Cyclopropyl-L-alanine; 2-Amino-3-cyclopropylpropanoic acid
EINECS	Contact for details

Quality Control

Our Cyclopropylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.