Description

n-(tert-Butoxycarbonyl)-L-Alanine is a protected amino acid derivative widely used as a crucial building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates for the production of pharmaceuticals and bioactive peptides. It is primarily utilized by the pharmaceutical, biotechnology, and fine chemical synthesis industries for developing therapeutic agents and complex organic molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental reagent for the sequential assembly of peptides, protecting the L-alanine amino group during chain elongation.
• Pharmaceutical Intermediate: Serves as a key starting material in the synthesis of active pharmaceutical ingredients (APIs) and peptide-based drugs.
• Bioconjugation: Used in the preparation of peptide-protein conjugates for diagnostic and therapeutic applications.
• Combinatorial Chemistry: Employed in libraries for drug discovery to create diverse arrays of peptide-like compounds.
• Biochemical Research: Acts as a standard or reagent in studies involving amino acid metabolism and protein engineering.
• Fine Chemical Production: Utilized in the custom synthesis of complex organic molecules requiring chiral, protected amino acid components.

Basic Information

Product Name	n-(tert-Butoxycarbonyl)-L-Alanine
CAS No.	15761-38-3
Molecular Formula	C8H15NO4
Molecular Weight	189.21 g/mol
Synonyms	Boc-L-Alanine; (S)-2-((tert-Butoxycarbonyl)amino)propanoic acid; N-Boc-L-alanine; Boc-Ala-OH; N-(tert-Butoxycarbonyl)-L-alanine; N-[(1,1-Dimethylethoxy)carbonyl]-L-alanine; L-Alanine, N-[(1,1-dimethylethoxy)carbonyl]-; tert-Butoxycarbonyl-L-alanine
EINECS	239-857-6

Quality Control

Our n-(tert-Butoxycarbonyl)-L-Alanine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) detailing specific results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.5%
Optical Rotation [α]20/D	-25° to -30° (c=1 in AcOH)
Chiral Purity (HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.