Description

α-Ethoxy-n-Methyl-n-[2-[Methyl(Phenethyl)Amino]Ethyl]-α-Phenylbenzeneacetamide CAS NO 15687-16-8 is a specialized organic compound belonging to the class of substituted amides and tertiary amines. This chemical is valued for its unique molecular architecture, which makes it a versatile intermediate in advanced synthetic chemistry. It is primarily sought after by research and development laboratories, as well as pharmaceutical manufacturers, for the synthesis of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and analgesic drug discovery programs.
• Chemical Research & Development: Serves as a crucial precursor for exploring new chemical entities (NCEs) and developing complex molecular structures in academic and industrial R&D settings.
• Fine Chemical Synthesis: Used in the multi-step synthesis of specialty chemicals, agrochemicals, and other high-value, low-volume organic compounds.
• Reference Standard: Employed as an analytical standard in method development and quality control for related pharmaceutical products and impurities.

Basic Information

Product Name	α-Ethoxy-n-Methyl-n-[2-[Methyl(Phenethyl)Amino]Ethyl]-α-Phenylbenzeneacetamide
CAS No.	15687-16-8
Molecular Formula	C28H34N2O2
Molecular Weight	430.58 g/mol
Synonyms	α-Ethoxy-N-methyl-N-[2-[methyl(phenethyl)amino]ethyl]-α-phenylbenzeneacetamide; 2-[Ethoxy(phenyl)methyl]-N-methyl-N-[2-[methyl(phenethyl)amino]ethyl]benzamide; Loperamide Impurity; Loperamide Related Compound; Loperamide Intermediate; 15687-16-8; N-Methyl-N-[2-[methyl(2-phenylethyl)amino]ethyl]-2-(phenyl)-2-(ethoxy)acetamide
EINECS	Contact for details

Quality Control

Our α-Ethoxy-n-Methyl-n-[2-[Methyl(Phenethyl)Amino]Ethyl]-α-Phenylbenzeneacetamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with client specifications and relevant ICH guidelines for impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.