Description

n-Methyl L-Z-Phenylalaninamide is a specialized chiral building block and modified amino acid derivative. This compound is of significant value in pharmaceutical research and development, particularly for the synthesis of peptides and peptidomimetics with enhanced metabolic stability and bioavailability. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, including enzyme inhibitors and receptor modulators.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of bioactive peptides and peptidomimetic drugs.
• Protease Inhibitor Development: Used in research for creating inhibitors targeting specific proteases.
• Medicinal Chemistry Research: Serves as a building block for structure-activity relationship (SAR) studies to optimize drug candidates.
• Bioconjugation: Potential use in the preparation of labeled compounds or antibody-drug conjugates (ADCs) for targeted therapies.
• Academic Research: Employed in universities and labs for studying peptide chemistry and molecular recognition.
• Custom Synthesis: Basis for the contract manufacturing of specialized, high-value fine chemicals for clinical trials.

Basic Information

Product Name	n-Methyl L-Z-Phenylalaninamide
CAS No.	15368-72-6
Molecular Formula	C18H20N2O3
Molecular Weight	312.37 g/mol
Synonyms	N-Methyl-L-phenylalaninamide, Z-L-Phe-NHMe; N-Methyl-N-benzyloxycarbonyl-L-phenylalaninamide; Z-Phe-NHMe; (S)-2-((Benzyloxy)carbonylamino)-N-methyl-3-phenylpropanamide; N-Carbobenzoxy-N-methyl-L-phenylalaninamide; N-Methyl-N-Cbz-L-phenylalaninamide; Nα-Methyl-Nα-Cbz-L-phenylalaninamide
EINECS	Contact for details

Quality Control

Our n-Methyl L-Z-Phenylalaninamide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.