Description

n-[3-(Trifluoromethyl)Phenyl]-1-Cyanoformamide is a specialized organic compound featuring a trifluoromethylphenyl group linked to a cyanoformamide moiety. This structure makes it a valuable high-purity intermediate for advanced chemical synthesis, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by research institutions, pharmaceutical manufacturers, and fine chemical producers engaged in creating novel molecules with enhanced biological activity and stability.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve lipophilicity and metabolic stability.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, or organic electronic materials due to its aromatic and polar functional groups.
• Chemical Biology & Proteomics: Can be utilized as a reactive handle or probe in biochemical research for studying enzyme inhibition or protein labeling.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis projects requiring the introduction of a specific trifluoromethylphenyl-cyanoformamide pharmacophore.

Basic Information

Item	Details
Product Name	n-[3-(Trifluoromethyl)Phenyl]-1-Cyanoformamide
CAS No.	15313-43-6
Molecular Formula	C9H5F3N2O
Molecular Weight	214.15 g/mol
Synonyms	3-(Trifluoromethyl)phenylcyanamide; 1-Cyano-1-[3-(trifluoromethyl)phenyl]formamide; α-Cyano-N-[3-(trifluoromethyl)phenyl]formamide; N-Cyano-N'-[3-(trifluoromethyl)phenyl]urea; (3-Trifluoromethylphenyl)cyanamide; 3-Trifluoromethylphenyl cyanamide; 3-(Trifluoromethyl)anilinocarbonitrile; 3-Trifluoromethylphenylcarbamoyl cyanide
EINECS	Contact for details

Quality Control

Our n-[3-(Trifluoromethyl)Phenyl]-1-Cyanoformamide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.