Description

(S)-(-)-α-Amino-γ-Butyrolactone Hydrobromide is a high-purity chiral building block and intermediate of significant importance in pharmaceutical synthesis. Its value lies in its role as a precursor for various active pharmaceutical ingredients (APIs) and fine chemicals, enabling the production of enantiomerically pure compounds. This product is essential for research institutions, pharmaceutical manufacturers, and fine chemical companies engaged in the development and production of novel therapeutics and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of various APIs, including nootropic agents and other central nervous system (CNS) active compounds.
• Asymmetric Synthesis: Used as a starting material or building block in asymmetric synthesis to introduce stereochemical complexity into target molecules.
• Nootropic Research: Serves as a critical precursor in the research and development of racetams and related cognitive-enhancing compounds.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals requiring specific stereochemistry.
• Academic & R&D: Utilized in university and corporate research laboratories for method development and exploratory chemistry projects.
• Process Chemistry: Applied in scale-up and process optimization studies for commercial pharmaceutical manufacturing routes.

Basic Information

Product Name	(S)-(-)-α-Amino-γ-Butyrolactone Hydrobromide
CAS No.	15295-77-9
Molecular Formula	C4H8BrNO2
Molecular Weight	182.02 g/mol
Synonyms	(S)-(-)-α-Amino-γ-butyrolactone hydrobromide; (S)-4-Amino-2-hydroxybutanoic acid γ-lactone hydrobromide; (S)-Amino-GBL HBr; (S)-(-)-2-Pyrrolidinone, 4-amino-, hydrobromide; (S)-4-Aminodihydro-2(3H)-furanone hydrobromide; (S)-(-)-4-Amino-2-butyrolactone hydrobromide; L-(-)-α-Amino-γ-butyrolactone hydrobromide
EINECS	Contact for details

Quality Control

Our (S)-(-)-α-Amino-γ-Butyrolactone Hydrobromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity, correct stereochemistry, and compliance with customer specifications. We provide comprehensive Certificates of Analysis (COA) detailing identity, purity (HPLC/Chiral HPLC), and impurity profiles. Our quality commitment supports applications in GMP-aligned environments and research requiring reliable, high-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container must be kept tightly sealed under dry, inert conditions to prevent moisture absorption. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.