Description

4,4,4-Trifluoro-1-(4-Methoxyphenyl)-1,3-Butanedione is a high-value fluorinated β-diketone building block. This compound is essential for its unique trifluoromethyl group, which imparts enhanced metabolic stability, lipophilicity, and bioavailability to target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a versatile chelating agent for metal ions in the preparation of catalysts for organic transformations.
• Material Science Research: Employed in the creation of fluorinated organic frameworks and polymers with specialized optical or electronic properties.
• Chemical Research & Development: A fundamental building block for exploring new fluorination chemistry and creating libraries of compounds for high-throughput screening.

Basic Information

Product Name	4,4,4-Trifluoro-1-(4-Methoxyphenyl)-1,3-Butanedione
CAS No.	15191-68-1
Molecular Formula	C11H9F3O3
Molecular Weight	246.18 g/mol
Synonyms	1-(4-Methoxyphenyl)-4,4,4-trifluorobutane-1,3-dione; 4,4,4-Trifluoro-1-(p-methoxyphenyl)-1,3-butanedione; 4'-Methoxy-2,2,2-trifluoroacetophenone; 4-Methoxyphenyl trifluoroacetyl methane; p-Methoxyphenyl trifluoroacetyl methane; TFMBD; 4,4,4-Trifluoro-1-(4-methoxyphenyl)butane-1,3-dione
EINECS	Contact for details

Quality Control

Our 4,4,4-Trifluoro-1-(4-Methoxyphenyl)-1,3-Butanedione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.