Description

3,5-Dichloro-L-Tyrosine is a halogenated derivative of the essential amino acid L-Tyrosine, characterized by the introduction of chlorine atoms at the 3 and 5 positions of the phenolic ring. This structural modification is critical for its role as a key synthetic intermediate and research chemical in advanced pharmaceutical development. It is primarily utilized by researchers and manufacturers in the life sciences sector for the synthesis of novel bioactive compounds and in biochemical studies investigating enzyme inhibition and receptor binding.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of more complex drug candidates, particularly in medicinal chemistry programs targeting neurological and metabolic disorders.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, especially those involving tyrosine kinases, hydroxylases, and decarboxylases.
• Peptide Synthesis: Incorporated into custom peptides to study the effects of halogenation on peptide structure, stability, and biological activity.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis using HPLC or LC-MS.
• Probe Development: Utilized in the design and development of molecular probes and diagnostic agents for imaging studies.

Basic Information

Product Name	3,5-Dichloro-L-Tyrosine
CAS No.	15106-62-4
Molecular Formula	C9H9Cl2NO3
Molecular Weight	250.08 g/mol
Synonyms	L-Tyrosine, 3,5-dichloro-; (2S)-2-Amino-3-(3,5-dichloro-4-hydroxyphenyl)propanoic acid; 3,5-Dichlorotyrosine; 3,5-DCl-Tyr; 3,5-Dichloro-4-hydroxyphenylalanine; NSC 403679; 3,5-Dichloro-L-tyrosine hydrate; 3,5-Dichlorotyrosine, L-
EINECS	Contact for details

Quality Control

Our 3,5-Dichloro-L-Tyrosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with key parameters including assay (HPLC), chiral purity, and impurity profiles. Our quality commitment supports applications in GMP-compliant research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity ([α]D)	≥ 99.0% L-Isomer
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.