Description

Methyl 2-Amino-2-Phenylacetate Hydrochloride is a high-purity, pharmaceutically relevant intermediate in the form of a stable hydrochloride salt. This compound is critical for the synthesis of complex molecules, offering a protected amino acid ester moiety essential for peptide coupling and chiral synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing active ingredients and novel compounds. Its consistent quality and reliable supply are paramount for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with peptide-like structures or chiral centers.
• Peptide Synthesis: Serves as a protected amino acid derivative for use in solid-phase and solution-phase peptide coupling reactions.
• Chiral Auxiliary/Resolution Agent: Utilized in asymmetric synthesis and for the resolution of racemic mixtures due to its inherent chirality.
• Agrochemical Research: Employed as a precursor in the development of novel herbicides, fungicides, and plant growth regulators.
• Fine Chemical Synthesis: Used in academic and industrial R&D for constructing complex organic molecules and exploring new chemical methodologies.
• Bioconjugation Chemistry: Acts as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.

Basic Information

Product Name	Methyl 2-Amino-2-Phenylacetate Hydrochloride
CAS No.	15028-40-7
Molecular Formula	C9H12ClNO2
Molecular Weight	201.65 g/mol
Synonyms	Methyl Phenylglycinate Hydrochloride; Methyl Aminophenylacetate Hydrochloride; (RS)-Methyl 2-Amino-2-phenylacetate Hydrochloride; DL-Methyl Phenylglycinate Hydrochloride; Methyl α-Aminophenylacetate Hydrochloride; Phenylglycine Methyl Ester Hydrochloride; 2-Amino-2-phenylacetic acid methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl 2-Amino-2-Phenylacetate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to ensure traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm
Residue on Ignition	≤ 0.1%
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.