Description

Acetamide, 2,2,2-Trifluoro-n-(3-Hydroxyphenyl)- is a specialized fluorinated aromatic amide building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a trifluoroacetamide group and a phenolic hydroxyl, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors. It serves as a critical precursor for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and inflammation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atoms can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Synthesis: Serves as a precursor for fluorinated components in electronic display and lighting materials.
• Polymer Modification: Incorporated into polymer chains to impart specific characteristics like chemical resistance or altered surface energy.
• Advanced Organic Synthesis: A versatile reagent for constructing complex heterocycles and other aromatic compounds in academic and industrial R&D.
• Chemical Biology Probes: Utilized in the creation of labeled compounds and probes for studying biological mechanisms.

Basic Information

Product Name	Acetamide, 2,2,2-Trifluoro-n-(3-Hydroxyphenyl)-
CAS No.	14983-08-5
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	N-(3-Hydroxyphenyl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-(3-hydroxyphenyl)acetamide; 3'-(Trifluoroacetylamino)phenol; 3-Hydroxytrifluoroacetanilide; m-Hydroxy-α,α,α-trifluoroacetanilide; TFAA-3-OH; Trifluoroacet-m-aminophenol; 14983-08-5
EINECS	Contact for details

Quality Control

Our Acetamide, 2,2,2-Trifluoro-n-(3-Hydroxyphenyl)- is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.