Description

4-Cyanopyridine n-Oxide is a versatile heterocyclic building block and a key intermediate in organic synthesis. This compound matters for its unique reactivity, where the electron-deficient cyano group and the electron-rich N-oxide moiety create a bifunctional platform for constructing complex molecular architectures. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug molecules, particularly those containing functionalized pyridine cores.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides that require specific pyridine-based structures.
• Ligand and Catalyst Development: Serves as a starting material for creating novel ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic semiconductors, conductive polymers, and other functional materials.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes and tags used in biochemical research and diagnostics.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions to form carbon-carbon and carbon-heteroatom bonds.

Basic Information

Product Name	4-Cyanopyridine n-Oxide
CAS No.	14906-59-3
Molecular Formula	C6H4N2O
Molecular Weight	120.11 g/mol
Synonyms	4-Cyanopyridine 1-Oxide; 4-Pyridinecarbonitrile 1-Oxide; Isonicotinonitrile N-Oxide; 4-Cyanopyridine N-Oxide; Pyridine-4-carbonitrile N-oxide; 4-Pyridyl cyanide N-oxide; Picolinonitrile 1-oxide (isomer); 4-Cyano-1-oxidopyridin-1-ium
EINECS	Contact for details

Quality Control

Our 4-Cyanopyridine n-Oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) that detail specifications such as assay (by HPLC), impurity profiles, and physical characteristics. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.