Description

Z-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-Betana is a synthetic peptide sequence of significant interest in biochemical research and pharmaceutical development. This compound is valued for its role as a substrate or inhibitor in enzymatic studies, particularly those involving proteases and other hydrolytic enzymes. It serves as a critical tool for researchers in pharmaceutical R&D, proteomics, and enzymology, enabling the investigation of enzyme kinetics, specificity, and the development of novel therapeutic agents.

Application

• Enzyme Substrate Research: Used as a specific chromogenic or fluorogenic substrate for studying the activity and inhibition of proteolytic enzymes like cathepsins and matrix metalloproteinases (MMPs).
• Drug Discovery & Development: Serves as a key intermediate or reference standard in the design and screening of peptide-based inhibitors for various disease targets.
• Biochemical Assay Development: Employed in the development and validation of high-throughput screening (HTS) assays to identify potential drug candidates.
• Proteomics & Peptide Mapping: Utilized as a model peptide in mass spectrometry and HPLC studies to understand peptide fragmentation patterns and separation techniques.
• Academic & Institutional Research: A fundamental reagent for universities and research institutes conducting basic research in biochemistry, cell signaling, and molecular biology.

Basic Information

Product Name	Z-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-Betana
CAS No.	14855-40-4
Molecular Formula	C58H78N10O13
Molecular Weight	1107.3 g/mol
Synonyms	Z-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-βNA; Benzyloxycarbonyl-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-β-Naphthylamide; Z-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-2-Naphthylamide; Cathepsin B Substrate (Z-Phe-His-Leu-Leu-Val-Tyr-Ser-βNA); Protease Substrate; Chromogenic Peptide Substrate; Fluorogenic Peptide Substrate; Z-Phe-His-Leu-Leu-Val-Tyr-Ser-βNA
EINECS	Contact for details

Quality Control

Our Z-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-Betana is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and chiral purity analysis. Certificates of Analysis (COA) detailing all test results are provided to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.