Description

(-)-n-(α-Cyano-4-Hydroxy-3-Methoxy-α-Methylphenethyl)Acetamide is a high-purity chiral intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Used as a precursor or catalyst ligand in stereoselective synthesis to construct complex molecules with high enantiomeric excess.
• Agrochemical Research: Serves as a building block for developing new chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Academic & R&D Laboratories: Employed in methodological studies and the discovery of new synthetic routes in organic and medicinal chemistry.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals where optical purity is a critical performance parameter.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(-)-n-(α-Cyano-4-Hydroxy-3-Methoxy-α-Methylphenethyl)Acetamide
CAS No.	14818-97-4
Molecular Formula	C14H16N2O3
Molecular Weight	260.29 g/mol
Synonyms	(-)-N-(α-Cyano-4-hydroxy-3-methoxy-α-methylphenethyl)acetamide; (R)-N-(1-Cyano-1-(4-hydroxy-3-methoxyphenyl)propan-2-yl)acetamide; (R)-N-[1-Cyano-1-(4-hydroxy-3-methoxyphenyl)propan-2-yl]acetamide; (R)-N-(1-Cyano-1-(4-hydroxy-3-methoxyphenyl)propyl)acetamide; (R)-N-[1-Cyano-1-(4-hydroxy-3-methoxyphenyl)propyl]acetamide; (R)-N-(α-Cyano-4-hydroxy-3-methoxy-α-methylphenethyl)acetamide; (R)-N-(1-Cyano-1-(4-hydroxy-3-methoxyphenyl)-1-methylethyl)acetamide; (R)-N-(1-Cyano-1-(4-hydroxy-3-methoxyphenyl)-1-methylpropyl)acetamide
EINECS	Contact for details

Quality Control

Our (-)-n-(α-Cyano-4-Hydroxy-3-Methoxy-α-Methylphenethyl)Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment. We can support development projects with custom purity grades and analytical data packages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.