Description

Acetamide, 2,2,2-Trifluoro-n-(2-Methoxyphenyl)- is a specialized fluorinated acetamide derivative, identified by CAS No. 14815-12-4, valued for its unique trifluoromethyl and methoxyphenyl functional groups. This compound serves as a critical building block and intermediate in advanced organic synthesis, enabling the introduction of fluorine atoms to modulate the properties of target molecules. It is primarily required by R&D and production teams in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or possessing enhanced metabolic stability.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides where the trifluoromethyl group can improve biological activity and environmental persistence.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis or organocatalysis.
• Material Science: Potential monomer or additive for synthesizing fluorinated polymers with specific thermal, chemical, or surface properties.
• Chemical Biology Probes: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a probe molecule in biochemical assays.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring fluorinated aromatic amides.

Basic Information

Product Name	Acetamide, 2,2,2-Trifluoro-n-(2-Methoxyphenyl)-
CAS No.	14815-12-4
Molecular Formula	C10H10F3NO2
Molecular Weight	233.19 g/mol
Synonyms	N-(2-Methoxyphenyl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-(2-methoxyphenyl)acetamide; 2-Methoxyphenyltrifluoroacetamide; α,α,α-Trifluoro-o-anisamide; o-Methoxyphenyltrifluoroacetamide; Trifluoroacetanisidide; TFAA-o-Anisidine Adduct; 2,2,2-Trifluoroacet-2'-methoxyanilide
EINECS	Contact for details

Quality Control

Our Acetamide, 2,2,2-Trifluoro-n-(2-Methoxyphenyl)- is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets precise customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The container should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.