Description

8-Chloro-10-[3-(Dimethylamino)Propyl]-10H-Phenothiazin-3-Ol Acetate is a high-purity, synthetically derived phenothiazine derivative. This compound is valued for its role as a critical pharmaceutical intermediate and research chemical in advanced organic synthesis. It is primarily required by manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and fine chemical sectors for developing active ingredients and novel molecular entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of antipsychotic and antihistamine drug candidates.
• Research & Development: Used in academic and industrial labs for studying phenothiazine chemistry and developing new therapeutic agents.
• Agrochemical Synthesis: Serves as a precursor in the development of specialized crop protection agents.
• Dye and Pigment Industry: Potential intermediate for creating specialized dyes and functional colorants.
• Material Science: Investigated for use in organic semiconductors and photoconductive materials.

Basic Information

Product Name	8-Chloro-10-[3-(Dimethylamino)Propyl]-10H-Phenothiazin-3-Ol Acetate
CAS No.	14734-77-1
Molecular Formula	C19H21ClN2O2S
Molecular Weight	376.90 g/mol
Synonyms	8-Chloro-10H-phenothiazin-3-ol, 10-[3-(dimethylamino)propyl]-, acetate (ester); 8-Chloro-10-(3-dimethylaminopropyl)phenothiazin-3-yl acetate; 8-Chloroprochlorperazine Acetate; Prochlorperazine Impurity; 8-Chloro-10-(3-dimethylaminopropyl)phenothiazin-3-ol acetate; NSC 77625; 14734-77-1
EINECS	Contact for details

Quality Control

Our 8-Chloro-10-[3-(Dimethylamino)Propyl]-10H-Phenothiazin-3-Ol Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specification results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to minimize exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.