Description

Acetamide, 2,2,2-Trifluoro-n-2-Propynyl- is a specialized fluorinated acetamide derivative, a high-value intermediate in advanced organic synthesis. Its unique structure, featuring both a trifluoroacetyl group and a propargyl moiety, makes it a critical building block for creating complex molecules with tailored properties. This compound is essential for R&D and production in the pharmaceutical and agrochemical sectors, where it is used to introduce fluorine atoms and reactive handles into target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of active pharmaceutical ingredients (APIs), particularly for introducing the trifluoroacetamide pharmacophore.
• Agrochemical Synthesis: Used in the research and manufacture of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and stability.
• Material Science Research: Acts as a precursor for novel fluorinated polymers, coatings, and liquid crystals with unique thermal and chemical resistance properties.
• Organic Synthesis Building Block: Utilized in click chemistry and other coupling reactions via its alkyne functionality for constructing complex molecular architectures.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new synthetic methodologies and creating novel fluorinated compounds.

Basic Information

Product Name	Acetamide, 2,2,2-Trifluoro-n-2-Propynyl-
CAS No.	14719-21-2
Molecular Formula	C5H4F3NO
Molecular Weight	151.09 g/mol
Synonyms	N-(2-Propynyl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-(prop-2-yn-1-yl)acetamide; N-Propargyl-2,2,2-trifluoroacetamide; 2,2,2-Trifluoroacetamide, N-2-propynyl-; Propargyl trifluoroacetamide; TFAA-Propargyl; Trifluoroacetic acid propargylamide
EINECS	Contact for details

Quality Control

Our Acetamide, 2,2,2-Trifluoro-n-2-Propynyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.