Description

8-Hydroxyquinoline Glucuronide is a key conjugated metabolite of 8-hydroxyquinoline, a compound with recognized chelating and antimicrobial properties. This glucuronide form is crucial for studying metabolic pathways, detoxification processes, and the pharmacokinetic profile of its parent compound. It serves as an essential reference standard and biochemical tool for researchers and quality control laboratories in the pharmaceutical, toxicology, and life science sectors.

Application

• Pharmaceutical Reference Standard: Used for the identification, purity assessment, and quantification of 8-hydroxyquinoline metabolites in drug development and bioanalytical studies.
• Metabolite Research: Critical for investigating Phase II metabolism, glucuronidation pathways, and the bioavailability of 8-hydroxyquinoline and related compounds.
• Toxicological Studies: Employed as a biomarker or standard in studies examining the excretion, detoxification, and safety profile of quinoline derivatives.
• Analytical Method Development: Serves as a high-purity calibrant for developing and validating HPLC, LC-MS, and other chromatographic assays in analytical laboratories.
• Biochemical Reagent: Used in enzymatic studies and in vitro assays to understand the activity of UDP-glucuronosyltransferase (UGT) enzymes.

Basic Information

Product Name	8-Hydroxyquinoline Glucuronide
CAS No.	14683-61-5
Molecular Formula	C₁₅H₁₅NO₈
Molecular Weight	337.28 g/mol
Synonyms	8-Hydroxyquinoline β-D-Glucuronide; 8-Hydroxyquinoline Glucuronide; 8-HQ Glucuronide; Quinolin-8-yl β-D-Glucopyranosiduronic Acid; 8-Hydroxyquinoline O-β-D-Glucuronide; 8-Hydroxyquinoline Glucuronoside; Glucuronide of 8-Hydroxyquinoline
EINECS	Contact for details

Quality Control

Our 8-Hydroxyquinoline Glucuronide is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the high standards required for research and reference applications. A detailed Certificate of Analysis (COA) with lot-specific data is provided to guarantee traceability and consistency for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.