Description

Pyrrolidine, 3-Methyl-1-(Trifluoroacetyl)- (8Ci,9Ci) is a specialized fluorinated pyrrolidine derivative, a key building block in advanced organic synthesis. Its core value lies in the trifluoroacetyl group, which introduces unique electronic and steric properties critical for modifying molecular reactivity and stability. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing novel active ingredients and complex fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine atoms can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and other sophisticated chemical transformations.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced materials with specific thermal, chemical, or surface properties.
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for studying biological mechanisms and enzyme interactions.
• Custom Synthesis and Process Development: A valuable starting material for contract research organizations (CROs) and companies engaged in custom synthesis and scale-up projects.

Basic Information

Product Name	Pyrrolidine, 3-Methyl-1-(Trifluoroacetyl)- (8Ci,9Ci)
CAS No.	14618-34-9
Molecular Formula	C7H10F3NO
Molecular Weight	181.16 g/mol
Synonyms	1-(Trifluoroacetyl)-3-methylpyrrolidine; 3-Methyl-1-(trifluoroacetyl)pyrrolidine; N-(Trifluoroacetyl)-3-methylpyrrolidine; 3-Methylpyrrolidine, 1-(trifluoroacetyl)-; 1-Trifluoroacetyl-3-methylpyrrolidine; 3-Methyl-N-(trifluoroacetyl)pyrrolidine; 1-(2,2,2-Trifluoroacetyl)-3-methylazolidine
EINECS	Contact for details

Quality Control

Our Pyrrolidine, 3-Methyl-1-(Trifluoroacetyl)- (8Ci,9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Specific Rotation (if applicable)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.