Description

D-α-Me-Phe.Hcl is a high-purity, non-natural amino acid derivative widely used in advanced pharmaceutical research and peptide synthesis. This compound is valued for its role in modifying peptide structure and function, enhancing metabolic stability and receptor selectivity. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors developing novel therapeutic peptides and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel peptide-based drugs and APIs.
• Peptide Synthesis: Used in Solid-Phase Peptide Synthesis (SPPS) and solution-phase methods to incorporate structural modifications.
• Biochemical Research: Serves as a tool compound in studying enzyme-substrate interactions, receptor binding, and metabolic pathways.
• Proteomics & Drug Discovery: Employed in the design and development of peptide libraries for high-throughput screening.
• Chiral Auxiliary/Resolution Agent: Utilized in asymmetric synthesis due to its defined stereochemistry.

Basic Information

Product Name	D-α-Me-Phe.Hcl
CAS No.	14603-77-1
Molecular Formula	C10H14ClNO2
Molecular Weight	215.68 g/mol
Synonyms	D-α-Methylphenylalanine hydrochloride; (R)-2-Amino-2-methyl-3-phenylpropanoic acid hydrochloride; D-2-Methylphenylalanine HCl; D-α-Me-Phe-OH·HCl; (R)-α-Methylphenylalanine hydrochloride; H-D-α-Me-Phe-OH·HCl; D-α-Methyl-Phe-HCl
EINECS	Contact for details

Quality Control

Our D-α-Me-Phe.Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.