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L-Glutamic Acid γ-(β-Naphthylamide) CAS NO 14525-44-1


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CAS No.:14525-44-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

L-Glutamic Acid γ-(β-Naphthylamide) is a specialized biochemical derivative of glutamic acid, where the γ-carboxyl group is linked to a β-naphthylamine moiety. This compound is valued for its role as a chromogenic substrate in enzymatic assays, particularly for detecting specific protease activity. It is primarily utilized by research institutions, diagnostic kit manufacturers, and pharmaceutical development laboratories requiring precise biochemical tools.

Application

  • As a chromogenic substrate for the detection and quantification of transglutaminase and other specific proteolytic enzymes.
  • In biochemical research for studying enzyme kinetics, inhibition, and mechanism of action.
  • For the development and quality control of in-vitro diagnostic (IVD) kits and reagents.
  • In pharmaceutical R&D for screening potential enzyme inhibitors as therapeutic candidates.
  • As a key intermediate or reference standard in the synthesis of more complex peptidomimetics and labeled compounds.

Basic Information

Product Name L-Glutamic Acid γ-(β-Naphthylamide)
CAS No. 14525-44-1
Molecular Formula C₁₅H₁₆N₂O₄
Molecular Weight 288.30 g/mol
Synonyms L-Glutamic Acid γ-(2-Naphthylamide); N5-(2-Naphthyl)-L-glutamine; γ-Glutamyl-2-naphthylamide; 2-Naphthylamide of L-Glutamic Acid; L-Glutamine, N-(2-naphthalenyl)-; N-2-Naphthyl-L-glutamine; Substrate for Transglutaminase; TGase Substrate
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Quality Control

Our L-Glutamic Acid γ-(β-Naphthylamide) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and diagnostic applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Optical Rotation [α]²⁰D: Specific range available on COA
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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