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L-Glutamic Acid γ-(β-Naphthylamide) CAS NO 14525-44-1
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CAS No.:14525-44-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
L-Glutamic Acid γ-(β-Naphthylamide) is a specialized biochemical derivative of glutamic acid, where the γ-carboxyl group is linked to a β-naphthylamine moiety. This compound is valued for its role as a chromogenic substrate in enzymatic assays, particularly for detecting specific protease activity. It is primarily utilized by research institutions, diagnostic kit manufacturers, and pharmaceutical development laboratories requiring precise biochemical tools.
Application
- As a chromogenic substrate for the detection and quantification of transglutaminase and other specific proteolytic enzymes.
- In biochemical research for studying enzyme kinetics, inhibition, and mechanism of action.
- For the development and quality control of in-vitro diagnostic (IVD) kits and reagents.
- In pharmaceutical R&D for screening potential enzyme inhibitors as therapeutic candidates.
- As a key intermediate or reference standard in the synthesis of more complex peptidomimetics and labeled compounds.
Basic Information
| Product Name | L-Glutamic Acid γ-(β-Naphthylamide) |
| CAS No. | 14525-44-1 |
| Molecular Formula | C₁₅H₁₆N₂O₄ |
| Molecular Weight | 288.30 g/mol |
| Synonyms | L-Glutamic Acid γ-(2-Naphthylamide); N5-(2-Naphthyl)-L-glutamine; γ-Glutamyl-2-naphthylamide; 2-Naphthylamide of L-Glutamic Acid; L-Glutamine, N-(2-naphthalenyl)-; N-2-Naphthyl-L-glutamine; Substrate for Transglutaminase; TGase Substrate |
| EINECS | Contact for details |
Quality Control
Our L-Glutamic Acid γ-(β-Naphthylamide) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and diagnostic applications. A detailed Certificate of Analysis (COA) is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Optical Rotation | [α]²⁰D: Specific range available on COA |
| Water Content (KF) | ≤ 1.0% |
| Residue on Ignition | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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