Description

Pyridoxal Phosphate γ-Glutamyl Hydrazone is a chemically modified derivative of pyridoxal 5'-phosphate (PLP), the active coenzyme form of vitamin B6. This compound is of significant interest in biochemical research due to its role as a potent inhibitor of enzymes dependent on PLP, particularly those involved in amino acid metabolism. It serves as a critical research tool for scientists and pharmaceutical developers in the fields of enzymology, metabolic pathway analysis, and drug discovery.

Application

• Enzymology Research: Used as a specific inhibitor to study the mechanism and function of pyridoxal phosphate-dependent enzymes, such as transaminases and decarboxylases.
• Metabolic Studies: Employed in laboratory investigations to modulate amino acid metabolism pathways, helping to elucidate their regulation and dysfunction.
• Pharmaceutical R&D: Acts as a reference standard or lead compound in the development of therapeutic agents targeting metabolic disorders or specific enzyme activities.
• Biochemical Assays: Serves as a key reagent in diagnostic or research assay kits designed to measure enzyme activity or screen for inhibitors.
• Nutritional Science Research: Used in studies exploring vitamin B6 biochemistry and the physiological impact of modulating its active coenzyme form.

Basic Information

Product Name	Pyridoxal Phosphate γ-Glutamyl Hydrazone
CAS No.	14520-50-4
Molecular Formula	C14H21N4O9P
Molecular Weight	420.32 g/mol
Synonyms	PLP-Glutamylhydrazone; Pyridoxal 5'-Phosphate γ-Glutamylhydrazone; γ-Glutamylhydrazone of Pyridoxal Phosphate; Vitamin B6 Coenzyme Inhibitor; 3-Hydroxy-5-(hydroxymethyl)-2-methyl-4-[[(1E)-[4-[[(2S)-1,5-dicarboxypentyl]amino]-4-oxobutylidene]hydrazinyl]methyl]pyridine 1-Oxide 5-(Dihydrogen Phosphate); 5'-Pyridoxal Phosphate γ-Glutamyl Hydrazone
EINECS	Contact for details

Quality Control

Our Pyridoxal Phosphate γ-Glutamyl Hydrazone is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency suitable for research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurities is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.