Description

n-Octadecanoyl-L-Valine is a high-purity, synthetic amino acid derivative where stearic acid (octadecanoic acid) is conjugated to the L-isomer of the amino acid valine. This compound matters as a versatile, lipophilic building block crucial for advanced research and development in pharmaceutical and cosmetic formulations, enabling the creation of novel peptide-mimetics and functional ingredients. It is primarily needed by R&D chemists and formulators in the pharmaceutical industry for prodrug development and by the personal care industry for creating sophisticated, skin-compatible actives.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel peptide-based drugs and prodrugs to enhance lipophilicity and membrane permeability.
• Cosmetic & Personal Care Actives: Used in the formulation of high-end skincare products as a conditioning agent or as a component of lipid-based delivery systems for other active ingredients.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and for investigating protein-lipid interactions due to its amphiphilic nature.
• Surfactant & Emulsifier Synthesis: Acts as a precursor for the development of specialized, mild surfactants with potential applications in niche industrial and cosmetic cleansers.
• Material Science: Investigated for creating functionalized surfaces, hydrogels, or polymers with specific biocompatible properties.

Basic Information

Product Name	n-Octadecanoyl-L-Valine
CAS No.	14379-32-9
Molecular Formula	C₂₃H₄₅NO₃
Molecular Weight	383.61 g/mol
Synonyms	L-Valine, N-(1-oxooctadecyl)-; Stearoyl-L-valine; N-Stearoyl-L-valine; N-Octadecanoylvaline; (2S)-2-[(1-Oxooctadecyl)amino]-3-methylbutanoic acid; N-(1-Oxooctadecyl)-L-valine; Octadecanoylvaline
EINECS	Contact for details

Quality Control

Our n-Octadecanoyl-L-Valine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity verification, to ensure it meets exacting standards for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% L-isomer
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.