Description

Sulfamonomethoxine-N1-Glucosiduronic Acid CAS NO 14365-51-6 is a key metabolite and reference standard of the sulfonamide antibiotic sulfamonomethoxine. This compound is essential for analytical and research applications, providing a critical benchmark for studying drug metabolism, pharmacokinetics, and ensuring accurate residue analysis. It is primarily required by pharmaceutical R&D laboratories, analytical service providers, and regulatory bodies involved in veterinary and human drug safety monitoring.

Application

• Pharmaceutical Reference Standard: Serves as a certified primary standard for the quantitative and qualitative analysis of sulfamonomethoxine and its metabolites in various matrices.
• Metabolite Research: Used in pharmacokinetic and metabolic pathway studies to understand the biotransformation and elimination of sulfamonomethoxine.
• Veterinary Drug Residue Testing: Critical for developing and validating analytical methods (e.g., HPLC, LC-MS/MS) to detect and quantify drug residues in food-producing animals to ensure food safety compliance.
• Quality Control in API Manufacturing: Employed as an impurity marker or system suitability standard during the quality control of sulfamonomethoxine active pharmaceutical ingredient (API) production.
• Clinical Toxicology: Utilized in forensic and clinical laboratories for the accurate identification and measurement of sulfonamide compounds in biological samples.
• Academic Research: Supports biochemical and pharmacological research into sulfonamide antibiotics, including studies on efficacy, resistance mechanisms, and environmental fate.

Basic Information

Product Name	Sulfamonomethoxine-N1-Glucosiduronic Acid
CAS No.	14365-51-6
Molecular Formula	C₁₇H₂₂N₄O₉S
Molecular Weight	458.45 g/mol
Synonyms	N1-(6-Methoxy-4-pyrimidinyl)sulfanilamide N1-Glucuronide; Sulfamonomethoxine Glucuronide; 4-Amino-N-(6-methoxy-4-pyrimidinyl)benzenesulfonamide N1-Glucuronide; Sulfamonomethoxine N1-β-D-Glucopyranosiduronic Acid; Sulfamonomethoxine Metabolite; SMM Glucuronide
EINECS	Contact for details

Quality Control

Our Sulfamonomethoxine-N1-Glucosiduronic Acid is manufactured and handled under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the high standards required for reference materials. A detailed Certificate of Analysis (COA) providing batch-specific results for identity, purity, and related substances is supplied with every product.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.