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H-Dl-Asp(Ome)-Ome Hcl CAS NO 14358-33-9


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CAS No.:14358-33-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

H-Dl-Asp(Ome)-Ome Hcl is a protected aspartic acid derivative, specifically the dimethyl ester hydrochloride salt of the DL-racemic mixture. This compound is a crucial building block (synthon) in organic synthesis, particularly for the preparation of peptides and peptidomimetics. It is essential for researchers and manufacturers in the pharmaceutical and biochemical sectors who require high-purity, protected amino acid precursors for drug discovery and development.

Application

  • Pharmaceutical Intermediate: A key starting material in the synthesis of complex peptide-based active pharmaceutical ingredients (APIs).
  • Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected aspartic acid residue to prevent unwanted side reactions.
  • Biochemical Research: Serves as a critical reagent in studying enzyme-substrate interactions, metabolic pathways, and protein structure-function relationships.
  • Prodrug Development: Utilized in the design and synthesis of prodrugs where the ester groups allow for controlled release or improved bioavailability.
  • Combinatorial Chemistry: Employed in the generation of diverse chemical libraries for high-throughput screening in drug discovery programs.
  • Agrochemical Research: Acts as a precursor in the development of novel peptide-inspired crop protection agents and herbicides.

Basic Information

Product Name H-Dl-Asp(Ome)-Ome Hcl
CAS No. 14358-33-9
Molecular Formula C7H14ClNO4
Molecular Weight 211.65 g/mol
Synonyms DL-Aspartic acid dimethyl ester hydrochloride; Aspartic acid dimethyl ester HCl; H-Asp(OMe)-OMe·HCl (DL); Dimethyl DL-aspartate hydrochloride; (RS)-2-Amino-1,4-butanedioic acid dimethyl ester hydrochloride; 2-Aminosuccinic acid dimethyl ester hydrochloride; Methyl DL-aspartate hydrochloride; Asp-OMe·HCl (DL)
EINECS Contact for details

Quality Control

Our H-Dl-Asp(Ome)-Ome Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Assay (HPLC) ≥98.0%
Water Content (KF) ≤1.0%
Residue on Ignition ≤0.1%
Heavy Metals ≤20 ppm
Optical Rotation (if applicable) Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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